In response to stress, the sympathetic nervous system (SNS) and hypothalamic-pituitary-adrenal (HPA) axis signal to the adrenals to release catecholamines (norepinephrine and epinephrine) and cortisol. Prolonged stress is associated with dysregulation of the HPA axis, which can affect catecholamine and cortisol levels.
Cortisol secretion follows a marked circadian pattern and increases in response to stress through activation of the HPA axis. Adipocytes (fat cells) play a major role in the body’s production of cortisol. High stress has been linked to less healthy dietary behaviors and increased body weight. Cortisol inhibits the secretion and actions of insulin (glucose uptake, central appetite reduction). Cortisol promotes the maturation of adipocytes (fat cells). Upregulation of the enzyme β-HSD1 promotes fat accumulation by increasing cortisol levels. Elevated bedtime cortisol levels are associated with increased abdominal fat.
Calm CP decreases cortisol levels and provides ingredients important for calm, sleep, and management of blood sugar.
Take 2 capsules one to two times daily or as directed by your healthcare provider. Do not exceed suggested use.
If you are pregnant or nursing, consult your healthcare provider before use.